A comprehensive, user-friendly guide to psychiatric medications. Multi-dimensional ratings from real patient reviews, clinical meta-analyses, and expert guidelines.
IMPORTANT MEDICAL DISCLAIMER
This website is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your psychiatrist, physician, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read here. Individual responses to medications vary enormously due to genetics, metabolism (CYP450 status), comorbidities, concurrent medications, age, and personal factors. Ratings are aggregated approximations from public sources and should never be used in isolation to start, stop, adjust, or compare treatments.
If you are in crisis, contact emergency services or a crisis hotline immediately (e.g., 988 in the US).
Filter, sort, and explore detailed profiles with complex multi-metric ratings.
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Transparent methodology for informed exploration
Drawn from network meta-analyses, large RCTs, guideline recommendations (APA, CANMAT, etc.), and real-world effectiveness data. Higher scores reflect stronger evidence for symptom reduction in the primary indication(s). Most first-line antidepressants cluster around 7.5–8.5 because differences are often modest between well-studied options.
Based on frequency and severity of adverse effects in clinical trials and post-marketing surveillance. Considers metabolic risk, extrapyramidal symptoms (EPS), sedation, sexual dysfunction, discontinuation difficulty, and serious but rare events. Lower scores for drugs requiring intensive monitoring (e.g., clozapine, lithium) or with high discontinuation rates due to side effects.
Primarily aggregated from verified user reviews on Drugs.com (thousands of reports per drug) supplemented by broader patient-reported outcome trends. Reflects perceived effectiveness vs. burden of side effects in everyday use. Note: Reviewers are self-selecting and may skew toward those with stronger experiences (positive or negative).
Overall score is a simple average of the three dimensions, rounded. All scores are approximations for educational use. They do not account for your unique biology, history, or preferences. Pharmacogenomic testing (e.g., GeneSight, OneOme) and therapeutic drug monitoring can further personalize choices. Therapy (CBT, IPT, etc.) combined with medication consistently shows superior outcomes for most conditions.